Body composition is associated with colorectal cancer (CRC) survival. However, body composition measurements have traditionally relied on single-slice, axial imaging. Fully automated volumetric body composition analysis is widely available, but associations with CRC survival have yet to be examined in detail.
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Performance of Pentixafor PET/CT in identifying unilateral primary aldosteronism: A meta-analysis
Primary aldosteronism (PA) is a clinical condition characterized by suppressedplasma renin activity (PRA), elevated plasma aldosterone concentration (PAC), and hypertension with or without hypokalemia, which are commonly resulting from aldosterone hypersecretion by lesions in the adrenal glands [1]. PA patients are at a high risk ofcardiovascular, cerebrovascular, and metabolic complications [2,3],underscoring the importance of effective control of aldosterone hypersecretion.
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MRI capacity assessment for prostate cancer screening in five regions of Europe
Prostate cancer (PCa) is the most common cancer among men in Europe and the third most common cause of cancer death in European men [1]. Screening by Prostate Antigen Test (PSA) in combination with MRI has shown potential in identifying clinically significant PCa [2–4]. It is reasonable to anticipate that the demand for MRI could increase further when screening programs are established. These advances led the European Union in December 2022 to recommend (‘recommendation 2′) to test and evaluate …
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Nomogram based on radiomics and CT features for predicting visceral pleural invasion of invasive adenocarcinoma ≤ 2 cm: A multicenter study
To explore the value of a nomogram based on radiomics and computed tomography (CT) features for preoperative prediction of visceral pleural invasion (VPI) of subpleural, small (≤2 cm) invasive adenocarcinoma (IAC) of the lung.
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Complications of transarterial radioembolization in hepatic malignancies: Pathophysiological insights and management paradigms
Hepatic malignancies constitute a formidable global health challenge, ranking as the sixth most commonly diagnosed cancer and the third leading cause of cancer-related mortality worldwide [1,2]. This heterogeneous disease spectrum primarily comprises primary hepatic neoplasms and metastatic liver lesions. Hepatocellular carcinoma (HCC), accounting for 75 %-85 % of primary liver malignancies [3], frequently evades early detection due to its insidious onset, resulting in frequent diagnosis at surg…
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Streamlining liver iron assessment: accuracy and limitations of 3D qDixon MRI for liver iron overload quantification
Iron overload is a major complication arising from chronic transfusion-dependent disorders or abnormal intestinal iron absorption, which can lead to multi-organ dysfunction [1]. Thalassemia serves as a classic example of transfusion-dependent diseases. Globally, approximately 1.5 % of the population carries the β-thalassemia gene, with over 300,000 individuals in China diagnosed with severe or intermediate forms of the disease [2]. Patients with severe β-thalassemia exhibit an exogenous iron int…
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Treatment response assessment in glioblastoma with GRASP DCE-MRI
Glioblastoma is the most common malignant brain tumor in adults, with higher incidence in males (4.09/100000) [1]. The current standard treatment involves maximal safe resection followed by concurrent radiochemotherapy [2].
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Association of intravascular enhancement sign on 3D T1- weighted TSE sequences with cerebral perfusion and infarction events in moyamoya disease
Moyamoya disease (MMD) is a chronic cerebrovascular disease characterized by progressive stenosis of the terminal internal carotid artery (ICA) and its proximal branches [1,2]. If not treated in time, it can lead to serious consequences such as death and disability. The specific pathogenesis of MMD is still unclear, and stroke is the main outcome event for patients, with cerebral ischemic symptoms being more common in clinical practice [3,4]. Early identification of risk factors related to cereb…
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Node-RADS 1.0 for lymph node involvement detection in renal cell carcinoma: A study on 2D and 3D CT imaging
Lymph node (LN) involvement (LNI) occurs in 30–40 % of patients with renal cell carcinoma (RCC) [1] and is an independent factor of poor prognosis for both advanced RCC and metastatic RCC [2,3]. Once LNI is identified, lymph node dissection (LND) or advanced treatment, including adjuvant therapy, is needed [4]. The American Urological Association and European Association of Urology have recommended LND with nephrectomy when clinically enlarged LNs are present for staging and prognostic assessmen…
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A machine learning approach for personalized breast radiation dosimetry in CT: Integrating radiomics and deep neural networks
While CT imaging provides indispensable volumetric information, it also involves exposure to ionizing radiation, which carries inherent risks. These risks are particularly significant for breast tissue, which is susceptible to radiation damage due to its high cellular turnover rate and sensitivity to the mutagenic effects of ionizing radiation [1,2]. Therefore, accurate estimation of radiation dose to the breasts during diagnostic CT imaging is essential for minimizing potential risks associated…