Colorectal cancer (CRC) is the second leading cause of cancer deaths globally [1,2], with significant implications for public health [1,2]. A thorough preoperative assessment of the colon is essential in CRC patients due to the risk of synchronous cancer, which occurs in 4.0 % to 6.0 % of cases [2–6]. Nevertheless, in cases of obstructive tumors, optical colonoscopy (OC), the gold standard for colorectal evaluation, may be incomplete [3,6–8]. In such cases, CT colonography (CTC) is recommended b…
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Peripheral vs. central parametric mapping of the liver in single ventricle patients: Measurement location matters
Patients with single ventricle anomalies undergo staged reconstructive heart surgery, resulting in a Fontan circulation. This circulation directly connects systemic venous return to the pulmonary arteries, creating a passive pulmonary circulation that bypasses the right heart. Hemodynamic changes following Fontan circulation affect the liver, leading to Fontan-associated liver disease (FALD), which begins to occur 5–15 years after palliation [1]. Furthermore, more than 40 % of survivors 30 years…
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MRI characteristics of FIGO stage IA epithelial ovarian cancer (EOC)
According to the Global Cancer Statistics 2022 data, ovarian cancer remains the fourth leading cause of death due to malignant tumors among women worldwide [1].
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Automated vertebrae identification and segmentation with structural uncertainty analysis in longitudinal CT scans of patients with multiple myeloma
Multiple Myeloma (MM) is an uncommon hematological malignancy characterized by uncontrolled proliferation of malignant plasma cells within the bone marrow, causing, among other symptoms, lytic bone lesions and deterioration of skeletal integrity [1]. Typically, the disease causes excessive bone resorption leading to vertebral compression fractures (VCFs), which 55 %-70 % of the patients suffer from at diagnosis [2]. The quality of life after such events decreases considerably, underscoring the i…
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Choroid plexus volume and association with migraine Pathophysiology
Direct evidence of choroid plexus structures involved in the presumed peripheral-central interaction in migraine is exceptionally scarce and, thus, which demands further attention.
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Identifying baseline rectal MRI features as predictive indicators for local recurrence and metastatic disease in rectal cancer treated with surgical resection and neoadjuvant therapy or surgical resection alone
Colorectal cancer is the third most common cancer worldwide and accounts for the second highest number of cancer deaths [1]. Of note, although the overall incidence of colorectal cancer has been decreasing in the past few years, there has been an increase in the incidence of colorectal cancer in patients younger than 50 years of age [1,2]. In the United States, colorectal cancer was responsible for 8.6 % of all cancer deaths in 2022 and the 5-year survival rate of colorectal cancer was 65.1 % fr…
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Diagnostic value of cardiac magnetic resonance imaging-based left atrial strain analysis for identifying cardiac diseases with overlapping phyotype
In recent years, the importance of quantifying atrial function and volumes in cardiomyopathies for diagnostic and prognostic purposes has been increasingly recognized. Left atrial (LA) size, volume, and functional parameters are linked to adverse clinical outcomes in cardiomyopathy patients [1,2,3]. However, LA contraction follows a complex sequence, which is not sufficiently described by volumes and conventional functional parameters alone [1,4]. LA contraction can be divided into three phases:…
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Tumor grade-titude: XGBoost radiomics paves the way for RCC classification
Renal cell carcinoma (RCC) is a common kidney malignancy, accounting for approximately 2.2 % of all newly diagnosed cancer cases worldwide [1]. Clear cell RCC is the most prevalent histologic subtype, constituting around 75 % of RCC cases [2]. The International Society of Urological Pathology (ISUP) grading system classifies RCC tumours into four grades, with the degree of nucleolar prominence assessed to determine grades 1–3 and the presence of highly atypical pleomorphic cells and/or sarcomato…
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Impact of Background Parenchymal Enhancement (BPE) on diagnostic performance of Contrast-Enhanced Mammography (CEM) for breast cancer diagnosis
This study investigates how background parenchymal enhancement (BPE) impacts diagnostic performance in interpretation of contrast-enhanced mammography (CEM) for breast cancer diagnosis.