A recent development in diagnosing total knee arthroplasty tibial component loosening uses Computed tomography (CT) images of loaded knees to assess implant micro-motion, but metal artefacts can affect reliability. This study investigates the impact of increased exposure and tube voltage, iterative metal artefact reduction reconstruction (iMAR), Sn-filtering and an extended CT scale (ECTS), compared to a standard knee CT protocol on load-induced implant displacement measurement.
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Prospective comparison of brain tumor detection and characterization using post-contrast Dixon uT1RESS and MPRAGE at 3 Tesla
Magnetic resonance imaging (MRI) is recognized as the most accurate modality for assessing brain tumors and is adept at evaluating lesion morphology and enhancement characteristics [1]. In particular, contrast-enhanced MRI provides essential information for monitoring disease progression and treatment efficacy, as well as for determining therapeutic strategies, such as surgical resection or radiotherapy, as these decisions rely heavily on the number, size, and location of intracranial lesions [2…
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Cost-effectiveness of [18F]FDG PET/CT in follow-up after thermal ablation in patients with colorectal liver metastases in the Dutch healthcare setting
Colorectal cancer (CRC) introduces a substantial health burden on patients and society due to its relatively high incidence and mortality [1]. In 2020, CRC was the third most commonly diagnosed cancer worldwide, accounting for about 10 % of all new cancer cases [2]. Moreover, CRC was the second leading cause of cancer mortality and accounted for 9.4 % of all cancer-related deaths [2]. Approximately 15–25 % of all patients with CRC history have metastatic disease (mCRC). The liver is the most com…
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Performance of MRI-based surveillance for high-risk individuals for pancreatic cancer
Pancreatic cancer (PC) is a lethal tumour with a 5-year survival rate of 11 % [1]. Although most PCs are sporadic, about 10 % of patients with PC are encountered among subjects with a strong family history or carrying predisposing germline mutations, defining these patients as high-risk individuals (HRIs). The risk of developing PC in these subjects varies depending on the family history and/or the specific underlying genetic mutation, ranging from a relative risk of about 2.5 to 132-fold higher…
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Comparison of image quality of 40 keV virtual monoenergetic images of vertebral arteries using DLIR and ASIR-V algorithms under a dual-low scanning protocol
This study aims to compare the image quality of 40 keV Virtual Monoenergetic Images (VMI) of the vertebral artery (VA) reconstructed using two algorithms, Deep Learning Image Reconstruction (DLIR) and Adaptive Statistical Iterative Reconstruction (ASIR-V), under a dual-low scanning protocol, which simultaneously reduces both the radiation dose and the contrast agent dose during the CT scanning process.
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Predictors of brain atrophy in focal epilepsy
Epilepsy is a disabling disease characterized by a wide variety of underlying pathologies, resulting in the common, crucial denominator of this illness, seizures. Even though numerous anti-seizure medications are available, one-third of patients still experience pharmaco-resistant epilepsy [1]. For these patients, surgery remains the final recourse. Yet, despite the promising prospects of seizure freedom in up to 64 % of the cases [2], resective surgery often remains an underutilized tool with s…
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Automatic prostate volume estimation in transabdominal ultrasound images
Prostate cancer is the second most common form of cancer in adult men, with approximately 1.4 million new cases diagnosed every year [3], with poorer patient prognosis if detected at later stages. Therefore, it is key to detect prostate cancer at an early stage, when treatment can be less invasive and with higher chance of successful cure. The current early prostate cancer diagnostic procedures revolve around different nomograms, aimed at quantifying prostate cancer risk based on clinically pred…
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Investigation of the relationship between mesorectal adipose tissue volume measured by computed tomography and histopathological prognostic features in patients with rectal cancer
The objective of this study was to examine the correlation between visceral adipose tissue (VAT) and mesorectal adipose tissue (MAT) volumes and poor prognostic factors, including extramural venous invasion (EMVI) and perirectal fat invasion (PFI).
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[18F]-FAPI-04 PET/CT improves metastatic lesions detection for patients with uterine malignancy after radical surgery: prospectively compared with [18F]-FDG PET/CT
This prospective study aims to investigate the potential of [18F]-fibroblast activation protein inhibitor ([18F]-FAPI)-04 PET/CT for evaluating suspected recurrent uterine malignancy after radical surgery, and prospectively compared with [18F]-Fluorodeoxyglucose ([18F]-FDG) PET/CT.