Non-alcoholic fatty pancreas disease (NAFPD) is generally defined as increased fat deposition in the pancreas [1], and is commonly associated with obesity and metabolic syndrome [2,3], as well as with metabolic dysfunction-associated steatotic liver disease (MASLD) [4–6]. While there is agreement on the impact of pancreatic steatosis on exocrine function [6–8], the effect of pancreatic steatosis on endocrine function is a widely discussed topic [8–11]. It is important to note that pancreatic fat…
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Research progress and clinical utility of multi-parameter orbital MRI in thyroid-associated ophthalmopathy
Thyroid-associated ophthalmopathy (TAO), also known as Graves’ ophthalmopathy, is a disfiguring and potentially sight-threatening autoimmune disease [1,2]. While it most commonly affects patients with Graves’ disease (approximately 90 % of cases), it can also manifest in patients who are euthyroid or hypothyroid. Its complex pathophysiology is driven by an autoimmune response targeting the thyrotropin (TSHR) and insulin-like growth factor-1 (IGF-1R) receptor complex on orbital fibroblasts. This …
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Preoperative MRI for non-invasive assessment of pancreatic acinar cell composition
This study explores the predictive power of preoperative MRI in evaluating pancreatic acinar cell composition. We aimed to determine whether MRI-derived signal intensity ratios could serve as reliable biomarkers for preoperative assessment.
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Diagnostic performance of Angio-Based fractional flow for hemodynamic assessment in intracranial Atherosclerosis
Intracranial atherosclerotic stenosis (ICAS) has been recognized as a common cause of stroke and transient ischemic attack (TIA), particularly in Asian populations [1,2]. Traditionally, a stenosis threshold of ≥ 70 % has been used to define severe intracranial atherosclerotic disease, largely based on landmark trials such as the Warfarin–Aspirin Symptomatic Intracranial Disease (WASID) and Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPR…
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Contrast enhanced ultrasound at first month: A feasible predictor for retreatment after benign thyroid nodule thermal ablation
Benign thyroid nodules (BTNs) are a common occurrence in the population [1]. The estimated prevalence of thyroid nodules in global is as high as 67 %, with nearly 90 % characterized as benign [2]. Clinical interventions typically deemed unnecessary in the majority of BTNs. However, palpable large BTNs necessitate treatment due to nodule-related compressive symptoms or cosmetic concerns [3]. Ultrasound (US)-guided thermal ablation (TA), encompassing modalities such as radiofrequency ablation (RFA…
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Head position matters: Position‑dependent vestibular flow void artifacts in inner ear MRI and their clinical implications
It has been shown that static magnetic fields from high-strength magnetic resonance imaging (MRI) machines induce nystagmus in all humans with intact inner ear function. This effect can be explained by the magneto-hydrodynamic Lorentz force, which arises from the interaction of endolymphatic ionic currents and the strong static magnetic field of an MRI machine. Prior experiments demonstrated that MRI-induced nystagmus and vertigo vary with head pitch relative to the magnetic field, being reduced…
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ChatGPT-5–Based large language model analysis versus an FDA-approved AI-CAD system for thyroid nodule ultrasound evaluation
Overdiagnosis and overtreatment of thyroid nodules remain pressing clinical concerns because a substantial proportion of surgically resected lesions prove benign on histopathology [1,2]. In the U.S., cancer statistics for 2025 estimate approximately 44,000 new thyroid cancer diagnoses and about 2,300 deaths, reinforcing its status as the most common endocrine malignancy and underscoring the need for precise preoperative risk stratification to minimize unnecessary surgery and guide surveillance […
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Evaluation of multi-keV PureCalcium images from photon-counting CT for abdominal imaging: A comparison with true and conventional virtual non-contrast images
To determine which keV PureCa images can effectively substitute TNC images for abdominal imaging.
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Evaluation of two software programs for cross‐sectional body composition analysis on abdominal computed tomography scans of patients with cirrhosis
The impact of body composition abnormalities and clinical outcomes in patients with cirrhosis is well established. Abdominal computed tomography (CT) evaluation is the technique that is better evaluated; however, agreements are not well known. Fifty patients were randomly selected from two centers, and two observers independently evaluated their CT. The cross-sectional muscle area (CSMA), skeletal muscle index (SMI), muscle attenuation (MA), visceral adipose tissue area (VAT), visceral adipose t…
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Development and characterization of new contrast agents for Photon-Counting CT
The visualization and characterization of benign and malignant structures using computed tomography (CT) is an integral part of clinical routine and thus, CT is one of the most important non-invasive imaging modalities available today [1–4]. The number of CT scans performed each year is approximately 300 million with an annual growth rate of 4 % [1]. A disadvantage of the current CT imaging technology, however, is the detection of the X-rays, which is conventionally performed using energy-integr…