SUMMARY:
Norrie disease is a rare X-linked condition characterized by early childhood blindness and later onset sensorineural hearing loss. We report two male infants with genetically confirmed Norrie disease and characteristic ocular abnormalities consisting of bilateral funnel retinal detachments, anterior segment dysgenesis, and/or buphthalmos and microphthalmia. MRI demonstrated enhancement of the cranial nerves, cochleae, and cerebellum with cerebellar restricted diffusion. Intracranial fin…
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Norrie Disease: Cochlear Enhancement and Cerebellar Signal Abnormalities [CLINICAL]
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Frontal Paraventricular Cysts: Refined Definitions and Outcomes [CLINICAL]
BACKGROUND AND PURPOSE:
Frontal paraventricular cystic changes have a varied etiology that includes connatal cysts, subependymal pseudocysts, necrosis, and enlarged perivascular spaces. These may be difficult to distinguish by neuroimaging and have a variety of associated prognoses. We aim to refine the neuroimaging definition of frontal horn cysts and correlate it with adverse clinical conditions.MATERIALS AND METHODS:
In this cross-sectional study, the pre- and postnatal neuroimaging databas… -
Radiologist, Trainee, and Logistical Factors Impacting the Timeliness of CTA Head and Neck Reporting in Stroke Code Activations [CLINICAL]
BACKGROUND AND PURPOSE:
Timely reporting of CTA examinations impacts management of acute vascular pathology such as large vessel occlusions, arterial dissection, and ruptured aneurysms, as well as a variety of acute nonvascular pathologies. In this study, we examine potential modifiable factors impacting the timeliness of CTA reporting performed in stroke code activations.MATERIALS AND METHODS:
This is an observational study of stroke code CTA head and neck examinations performed at a single h… -
Cavernous Sinus Dural Arteriovenous Fistula: Treatment via the Transfemoral Transfacial Route [CLINICAL]
Cavernous sinus dural arteriovenous fistulas (dAVFs) are most frequently treated by a transvenous approach via the inferior petrosal sinus (IPS). However, in certain patients, the IPS is not amenable to navigation. In this technical video, we present the case of a patient with a cavernous sinus dAVF embolized by the transfemoral transfacial venous route on a failed attempt to catheterize the IPS. Preprocedural head and neck imaging was performed, documenting the facial vein draining to the inter…
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In Vivo Visualization of Charcot-Bouchard Aneurysms on Lenticulostriate Arteries Using 7T MRI [RESEARCH]
BACKGROUND AND PURPOSE:
Charcot-Bouchard aneurysms (CBAs) are tiny aneurysms arising from small perforating arteries. Despite the potentially catastrophic consequences of rupture of these aneurysms, the existence and prevalence of CBAs are controversial. The literature in this area is sparse with most previous studies based on radiologic case reports of single hemorrhage or histopathologic analysis. 7T MRI provides higher spatial resolution than 3T MRI, which enables imaging of the small perfora… -
Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques [CLINICAL]
BACKGROUND AND PURPOSE:
Photon-counting detector CT myelography (PCD-CTM) is a recently described technique used for detecting spinal CSF leaks, including CSF-venous fistulas. Various image reconstruction techniques, including smoother-versus-sharper kernels and virtual monoenergetic images, are available with photon-counting CT. Moreover, denoising algorithms have shown promise in improving sharp kernel images. No prior studies have compared image quality of these different reconstructions on p… -
Difficulties in Transvenous Embolization via the Cavernous Sinus: Buddy-Wire Anchoring Technique [CLINICAL]
The cavernous sinus drains venous blood from most of the temporal lobe through the superficial middle cerebral vein (SMCV).1 Brain AVMs located on the surface of the temporal and parietal lobes often drain into the SMCV.2 Therefore, in cases treated with transvenous embolization, accessing the SMCV passing through relaying the cavernous sinus (CS), which can interfere with the deployment of the microcatheter by trapping the catheter in the CS. In this video article, we describe a bailout techniq…
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Worlds First Real-Time Artificial Intelligence-Assisted Mechanical Thrombectomy for Acute Ischemic Stroke [ARTIFICIAL INTELLIGENCE]
SUMMARY:
Several recent reports have discussed real-time artificial intelligence (AI) assistance in elective neuroendovascular procedures such as carotid artery stent placement, coil embolization for cerebral aneurysms, and liquid embolization. We present our preliminary experience with real-time AI-assisted mechanical thrombectomy (MT) for acute ischemic stroke (AIS) under local anesthesia. A real-time deep learning–based AI software (Neuro-Vascular Assist, iMed Technologies) was used dur… -
Slice-to-Volume Reconstruction of Fetal Brain MR Imaging in Clinical Practice [CLINICAL]
SUMMARY:
Slice-to-volume reconstruction (SVR) is used to generate 3D isotropic high-resolution MR images from multiple 2D stacks to correct for fetal motion. The purpose of this study is to develop an automated SVR pipeline for integration into clinical workflow. This prospective, institutional review board–approved study included pregnant women undergoing fetal MRI. In addition to standard of care (SOC), which includes 2D T2-single-shot fast spin echo (SSFSE) contiguous images at 3–… -
The Brush Sign Is Associated with a More Severe Oxygen Metabolic Impairment of the Ischemic Penumbra: An MRI-Based Study in Patients with Acute Stroke [CLINICAL]
BACKGROUND AND PURPOSE:
In acute stroke, the brush sign has been linked to an increased risk of hemorrhagic transformation. We aimed to assess the oxygen metabolic abnormalities occurring in patients with acute ischemic stroke (AIS) exhibiting the brush sign on admission MRI and its prognostic value at follow-up.MATERIALS AND METHODS:
We retrospectively analyzed data from the Cohort of Patients to Identify Biological and Imaging Markers of Cardiovascular Outcomes in Stroke cohort (NCT: 0314970…