BACKGROUND:
Intracranial aneurysms (IAs) are the major cause of subarachnoid hemorrhage. Stent-assisted coiling, especially with the Neuroform Atlas stent (NAS), has proved more effective than coiling alone for treating these aneurysms.

PURPOSE:
To perform a systematic review and meta-analysis to investigate the efficacy and safety of the NAS in treating IAs.

DATA SOURCES:
A comprehensive literature search was conducted on PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and cli…

Read the full article on ajnr.org

BACKGROUND AND PURPOSE:
There is surging interest in the therapeutic potential of psychedelic compounds like psilocybin in the treatment of psychiatric illnesses like major depressive disorder (MDD). Recent studies point to the rapid antidepressant effect of psilocybin; however, the biologic mechanisms underlying these differences remain unknown. This study determines the feasibility of using diffusion MRI to characterize and define the potential spatiotemporal microstructural differences in the…

Read the full article on ajnr.org

SUMMARY:
We propose a novel application of MR encephalography (MREG) to detect the frequency spectrum of endogenous slow oscillatory brain activity (delta, <4 Hz). MREG offers faster image acquisition than conventional fMRI and superior spatial localization than electroencephalography/magnetoencephalography. MREG was acquired at a 0.1-second temporal resolution in a healthy adult during interleaved wakefulness and sleep to demonstrate its capability for detecting delta-band power changes asso…

Read the full article on ajnr.org

BACKGROUND AND PURPOSE:
2D linear measurements are often used in routine clinical practice during vestibular schwannoma (VS) follow-up, primarily due to wider availability and ease of use. We sought to determine the radiologist’s performance compared with 3D-volumetry, along with the impact of the number of linear measurements, slice thickness, and tumor volumes on these parameters.

MATERIALS AND METHODS:
Specificity and accuracy estimates and 95% confidence intervals were calculated for …

Read the full article on ajnr.org

BACKGROUND AND PURPOSE:
This retrospective study evaluated the utility of contrast-enhanced T1-weighted 3D fast spin-echo–based sampling perfection with application-optimized contrasts by using different flip angle evolutions (SPACE) sequences for brain metastasis detection on 3T MRI compared with a gradient-recalled echo–based 3D FLASH sequence.

MATERIALS AND METHODS:
We identified all patients at a single institution who underwent SPACE and 3D FLASH sequences as part of a practice…

Read the full article on ajnr.org

BACKGROUND AND PURPOSE:
Single large-scale mitochondrial deletion syndrome (SLSMD) comprises devastating mitochondrial diseases often classified into 3 major clinical syndromes: Kearns-Sayre syndrome (KSS), chronic progressive external ophthalmoplegia (CPEO), and Pearson syndrome (PS). Nevertheless, there remains large clinical variability and overlap among these SLSMD groups. Therefore, further stratification is required for more precise prognostication and clinical management. Through detailed…

Read the full article on ajnr.org

BACKGROUND AND PURPOSE:
Neoadjuvant BRAF-directed therapy and immunotherapy followed by surgery improves survival in patients with BRAFV600E-mutant anaplastic thyroid carcinoma (ATC), more so in those who have complete ATC pathologic response. This study assesses the ability of FDG-PET to noninvasively detect residual high-risk pathologies including ATC and poorly differentiated thyroid carcinoma (PDTC) in the preoperative setting.

MATERIALS AND METHODS:
This retrospective, single-center study …

Read the full article on ajnr.org

SUMMARY:
Imaging can help to diagnose CNS vasculitis. Yet so far, no imaging studies of CNS vasculitis at 7T are available. We share our experience of vessel wall imaging (VWI) at 7T in patients with suspected vasculitis. All included patients (n=45) underwent a clinically approved 7T MRI comprising high-resolution arterial TOF angiography as well as high-resolution VWI with T1 sampling perfection with application-optimized contrast using different flip angle evolution (SPACE) and T1 SE acquired…

Read the full article on ajnr.org