To evaluate a deep-learning algorithm for automated coronary artery analysis on ultrahigh-resolution photon-counting detector coronary computed tomography (CT) angiography and compared its performance to expert readers using invasive coronary angiography as reference.
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An in-depth analysis of coronary computed tomography angiography segmental findings in acute spontaneous coronary artery dissection – a prospective multicenter study
Spontaneous coronary artery dissection (SCAD), causing acute coronary syndrome (ACS), primarily in middle-aged women, is diagnosed with invasive coronary angiography (ICA). Due to the risk of dissection propagation with ICA, a non-invasive diagnostic tool is needed. We investigated coronary computed tomography angiography (CCTA) findings in acute SCAD, as well as the inter-modality agreement between CCTA and ICA.
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Evaluating the CT-STEMI study: The controversy over CCT and CMR for post-STEMI prognosis
I have read with great interest the recent publication by Marco Gatti et al. entitled “Rationale and design of the CT-STEMI study (Cardiac Computed Tomography for comprehensive risk stratification of arrhythmic, atherothrombotic and heart failure events following reperfused ST-segment Elevation Myocardial Infarction)”.1 The goal of this study was to evaluate the accuracy of cardiac computed tomography (CCT) and its prognostic relevance compared with cardiac magnetic resonance (CMR) in post-STEMI…
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Coronary Computed Tomography Angiography (CCTA) utilization in acute Spontaneous Coronary Artery Dissection (SCAD) hospitalizations in the United States from 2017 to 2022
Spontaneous Coronary Artery Dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome.1 Invasive coronary angiography (ICA) is the gold standard for diagnosing SCAD, while coronary computed tomography angiography (CCTA) offers a noninvasive 3-dimensional assessment. Although CCTA is not yet a first-line modality for SCAD due to lower spatial and temporal resolution than ICA, it is often performed for diagnostic confirmation or to assess vessel healing during hospitalizatio…
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Comparative evaluation of CTCA and TOE in the detection of paravalvular complications in prosthetic valve endocarditis
Prosthetic valve infective endocarditis (PVE) is one of the most severe complications after valve implantation. Early diagnosis and identification of paravalvular complications are essential to determine optimal timing of surgery. Our aim is to assess the diagnostic performance of Computed Tomography Coronary Angiography (CTCA) versus Transoesophageal echocardiography (TOE) for the detection of valvular and paravalvular complications of PVE against the reference standard of surgical inspection.
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Three-dimensional left atrial strain from retrospective gated computed tomography: Comparison with speckle-tracking echocardiography in patients with aortic stenosis
Three-dimensional (3D) left atrial (LA) deformation assessment beyond the two-dimensional (2D) apical views circumvents atrial foreshortening and can be quantified from four-dimensional (4D) retrospective gated computed tomography (CT) using novel feature tracking methods. However, the consistency between CT-derived 3D and echocardiographic 2D peak left atrial longitudinal strain (PALS) has not been reported. We aimed to compare CT-derived 3D and echocardiographic 2D PALS in patients undergoing …
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Cardiac CT fractal analysis of LV noncompaction and common cardiomyopathies
Left ventricular noncompaction (LVNC), or hypertrabeculation, is a myocardial condition that remains challenging to diagnose and differentiate from other cardiomyopathies. This study evaluated the ability of cardiac CT to differentiate between LVNC, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and controls using fractal analysis of LV trabeculae.
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The effect of metoprolol on heart rate before coronary CT angiography: Lessons and recommendations from a large cohort
Coronary CT angiography (CCTA) is the recommended initial test for most patients with suspected coronary artery disease (CAD).1 In preparation for CCTA, lowering the heart rate (HR) is essential to optimize image quality, reduce radiation exposure, and enable advanced techniques such as CT-derived fractional flow reserve – even with modern CT scanners.2–4 A target HR of <60 beats per minute (bpm) during CCTA is recommended for commonly used scanners, primarily to minimize motion-related artif…
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Intravenous metoprolol and diltiazem drug combination therapy for heart rate control in coronary CT angiograms
Heart rate control by metoprolol yields better image quality for CT coronary angiograms (CTCA). When metoprolol fails to satisfactorily reduce heart rate, drug combinations can be used. The safety profile of combining metoprolol and diltiazem for CTCA is unknown but known risks include atrioventricular nodal block, bradycardia, hypotension and heart failure.1,2
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AI-enabled opportunistic left ventricular volumetry in coronary artery calcium scans predicts heart failure comparably to cardiac MRI: An AI-CVD study with the Multi-Ethnic Study of Atherosclerosis (MESA)
Artificial intelligence applied to coronary artery calcium (CAC) scans can provide information beyond what is currently reported. The AI-CVD initiative aims to opportunistically extract all actionable information from CAC scans and lung scans. We have recently shown that AI-CVD opportunistic screening for enlarged cardiac chambers particularly left atrium (LA) and left ventricle, and increased left ventricular (LV) mass in CAC scans predicts future atrial fibrillation (AF) and heart failure (HF)…