Computed tomography angiography (CTA) is a widely used diagnostic tool, but concerns about radiation exposure necessitate accurate dose estimation. This study investigates the correlation between Effective Dose (ED) and Size-Specific Dose Estimate (SSDE) estimated from the patient’s body mass index (BMI) in CTA to evaluate the utility of SSDE-BMI as a patient-specific dosimetry parameter.
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Background parenchymal enhancement as a predictor of invasive disease-free survival in hormone receptor-positive, HER2-negative breast cancer
The Oncotype DX assay (Genomic Health), a commercially available 21-gene breast cancer recurrence score (RS) assay, is one of several gene-expression assays that are used to predict prognosis in hormone receptor-positive breast cancer [1]. The Oncotype DX assay provides RS values ranging from 0 to 100, with higher scores indicating a worse prognosis and a greater likelihood of benefiting from chemotherapy [2]. A high RS, defined as 31 or higher (or 26 or higher in some cases), suggests a potenti…
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The new frontier of MRI: Virtual dissection with 3DPDw sequence. A pilot study on ATiFL anatomy
There is much conflicting data regarding the anatomy of the anterior tibiofibular ligament (ATiFL), even in studies with anatomical specimens. Therefore, this study aims to reassess the anatomy of this ligament using a high-resolution isotropic 3D-PDw MRI sequence.
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Application of contrast-enhanced ultrasound in the diagnosis of liver solid-cystic lesions
Liver solid-cystic lesions are diverse in type, and accurate differential diagnosis is of great clinical significance. This study aimed retrospectively analyze the sonographic features of conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS) in liver solid-cystic lesions, and to compare their diagnostic performance
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Cardiovascular magnetic resonance characteristics of focal takotsubo syndrome
Focal takotsubo syndrome (TTS) is rare, and limited data are available on its cardiovascular magnetic resonance (CMR) characteristics. We aimed to define CMR characteristics and disease patterns of focal TTS.
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Role of FAPI PET/CT in cancer of unknown primary (CUP): A systematic review
Patients with a cancer of unknown primary (CUP) are a heterogeneous population in whom the origin of a metastatic malignant disease cannot be determined after standardized diagnostic work-up. CUP accounts for 3–5 % of all malignant neoplasms worldwide [1,2].
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Predicting peritoneal recurrence and hyperthermic intraperitoneal chemotherapy benefits in T4 gastric cancer patients via contrast-enhanced CT radiomics
Despite advances in surgical techniques and molecular targeted therapy, gastric cancer (GC) remains one of the most lethal malignancies worldwide, causing 750,000 deaths annually [1–3]. Tumor recurrence in the peritoneum occurs in 40 %–60 % of advanced GC patients who have undergone radical surgery [4–6], and patients who develop peritoneal recurrence (PR) have a median overall survival (OS) of only 3–9 months [7,8]. Therefore, timely and appropriate preventive interventions to reduce the risk o…
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Deep learning-based temporal muscle quantification on MRI predicts adverse outcomes in acute ischemic stroke
Stroke is the second-leading cause of death and the third most common cause of disability worldwide [1]. Stroke significantly increases the risk of skeletal muscle loss (known as sarcopenia), which exacerbates disability and worsens functional outcomes. Pre-stroke sarcopenia has also been linked to poorer recovery, thereby underscoring the importance of evaluating muscle mass and function in stroke patients [2–5]. Measuring skeletal muscle mass and function is increasingly recognized as a critic…
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Photon counting CT versus multi-slice CT for radiographic evaluation of postoperative cochlear implantation: Electrode characteristics and image-quality analysis
Cochlear implant surgery is a standard treatment for severe-to-profound hearing loss. Accurate postoperative assessment of cochlear electrode is crucial for patient outcomes. Photon-counting CT (PCCT) has emerged as a novel imaging modality that may surpass multi-slice CT (MSCT) in image quality and metal artifact reduction. This study aimed to compare PCCT and MSCT in the radiographic evaluation of postoperative cochlear implantation.
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NAVIGATOR: A regional multimodal imaging biobank initiative powered by AI tools for precision medicine in oncology
Biobanks play a crucial role in advancing biomedical research by enabling the collection, storage, and sharing of vast amounts of clinical and imaging data [1]. Across Europe, numerous biobank initiatives, often supported by the European Union, have emerged to foster collaborative research and drive innovation in precision medicine [2]. These platforms are essential for integrating multimodal data to improve disease characterization, therapeutic decision-making, and prognostic evaluation. The NA…