History taking and physical examination are considered the cornerstones of medical diagnosis [1]. They raise the probability of a certain diagnosis or differential diagnosis, which increases the yield of subsequent diagnostic tests, such as imaging [1]. However, it has been recognized that the quality of physical examination, if performed at all, has been declining over the past decades [1,2]. This decline can be attributed to several factors, including the availability of advanced diagnostic te…
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Development and validation of multiparametric models incorporating 18F-FDG PET/CT dissemination characteristic for predicting outcomes of small cell lung cancer
To evaluate the prognostic value of the tumor dissemination characteristic, metabolic parameters from baseline 18F-FDG PET/CT, clinical indicators, and pathological indicators in small cell lung cancer (SCLC), and to construct prognostic models.
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Periportal halo on early postoperative CT predicts biliary complications following liver transplantation
Biliary complications remain the leading non-vascular cause of morbidity, re-intervention and graft loss after liver transplantation (LT). Previous series have suggested that a “periportal halo” (PPH) on early post-operative CT might herald later graft dysfunction, but its prognostic value has never been quantified in a contemporary cohort.
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Evaluation of diffusion-weighted imaging datasets for the assessment of disease activity in lymphoma patients
Lymphomas are a heterogeneous group of neoplasms of the lymphatic system. Accurate staging of lymphoma patients is essential for the selection of a suitable treatment strategy and the assessment of the patient’s prognosis. Within the last decades, Positron-emission-tomography/Computed-tomography (PET/CT) systems have been successfully introduced into clinical imaging algorithms [1]. Combining functional and morphological information has been found more accurate for lesion detection and whole-bod…
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Potential values of uEXPLORER total-body PET/CT in nasopharyngeal carcinoma: dynamic imaging and kinetic parameters
To explore the dynamic imaging and kinetic parameters of total-body positron-emission tomography/computed tomography (TB-PET/CT) in nasopharyngeal carcinoma (NPC).
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Measuring the impact of using 3D helical scout scans on overscan and radiation exposure
Scout scans are an essential part of the workflow in CT imaging, enabling the accurate positioning of the scan range for the main acquisition. Traditionally, these low-dose, lower-quality 2D images are acquired using a static X-ray tube, which captures anatomical features in a specified imaging plane to set the scan range appropriately and ensure accurate patient positioning. However, standard 2D scouts limit the accuracy of the planned scan range and patient position due to the visibility of an…
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Multimodal radiomic analysis to determine high-Consistency prognostic phenotypes associated with epidermal growth factor receptor mutations in non-small cell lung cancer brain metastases
Limited linkage between epidermal growth factor receptor (EGFR) mutations and recurrence–predictive radiomic signatures restricts the application of radiomics–guided therapy for brain metastases (BMs) from non–small–cell lung cancer (NSCLC). This study aimed to establish an EGFR-associated radiomic signature (EGFR-RS), compare its consistency with that of conventional whole radiomic features-based radiomic signature (WF-RS), and evaluate its efficacy in predicting local recurrence for BMs treate…
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Fully automatic bile duct segmentation in magnetic resonance cholangiopancreatography for biliary surgery planning using deep learning
Complications from complex biliary surgery, including live donor liver transplantation, radical resection of biliary tumors, and hepatectomy for hepatolithiasis, occur at a high rate of up to about 30 % [1–4], which mainly consist of biliary injury, bleeding, bile fistula, and biliary stricture. These complications can severely impact patients’ surgical outcomes, quality of life, and even endanger their lives. A key reason is the intricate and variable anatomical structure of the intrahepatic bi…
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Deep learning based multi-shot breast diffusion MRI: Improving imaging quality and reduced distortion
Breast magnetic resonance imaging (MRI) is the most effective method for detecting breast cancer compared to other imaging techniques [1]. In multiparametric breast MRI, diffusion-weighted imaging (DWI) is a commonly used technique, which can distinguish between malignant and benign findings by measuring the diffusivity of water molecules, quantified as the apparent diffusion coefficient (ADC) [2]. Breast malignancies exhibit lower water molecule diffusivity compared to normal breast tissue due …
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Cerebral collateral cascade associated with infarct growth rate in ischemic stroke patients undergoing endovascular treatment
Variability in infarct growth rate(IGR) is strongly associated with clinical outcomes in acute ischemic stroke(AIS) patients receiving endovascular treatment(EVT). Recently, the cerebral collateral cascade(CCC) has been shown to be related to imaging and clinical outcomes in AIS. Therefore, we investigated the association between CCC and IGR.