Auriculocondylar syndrome (ACS; MIM 602483), also known as “question-mark ear syndrome” or “dysgnathia complex,” is a rare autosomal dominant craniofacial malformation syndrome. It is characterized by variable mandibular anomalies ranging from mild micrognathia to severe mandibular hypoplasia, cleft palate, and a distinctive auricular malformation consisting of lobule–helix separation, producing the “question-mark ear” (QME) appearance (Figs. 1, 2) [1–3]. Additional commonly reported features in…
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Quantitative sonazoid contrast-enhanced ultrasound features for predicting microvascular invasion of hepatocellular carcinoma
Primary liver cancer was the sixth most common cancer and the third leading cause of death worldwide in 2020 [1], and hepatocellular carcinoma (HCC) represents the leading primary malignant liver tumor with a poor prognosis. Microvascular invasion (MVI) is an independent predictor closely associated with aggressive biological behavior and poor outcomes [2]. The preoperative identification of MVI status is clinically important to optimize HCC treatment strategies and improve long-term survival, i…
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Risk factors associated with immediate hypersensitivity reaction to contrast media: a systematic review and meta-analysis
Hypersensitivity reaction (HR) is a subtype of adverse drug responses that are unpredictable and characterized by symptoms and/or signs triggered by a drug dose that is generally well tolerated by healthy individuals. Patients typically present with manifestations resembling allergic reactions, such as urticaria, pruritus, angioedema, erythema, and anaphylaxis [1,2]. With the increasing use of contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), contrast media (CM) ad…
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Four-dimensional CT analysis of patellofemoral instability: A prospective cohorte study
To evaluate a semiautomatic quantitative analysis approach using 4D CT for patellofemoral joint motion in patients with and without instability risk factors by classifying them into four subgroups: patellofemoral pain syndrome (PFPS), potential patellar instability (PPI), objective patellar instability (OPI) and control.
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Over-scanning in pediatric head CT: prevalence, dosimetric impact, and associated cancer risks
Brain CT is the most frequently performed CT scan among children. The increasing reliance on computed tomography (CT) in pediatric clinical practice has raised major concerns regarding radiation-induced cancer risks [1–3]. Although the brain is relatively less radiosensitive than many other organs, children are particularly more susceptible to radiation-related harm due to their smaller body size, greater tissue sensitivity, and longer post-exposure life expectancy [4,5]. Studies have shown that…
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Evaluating the impact of sigmoid sinus wall reconstruction on pulsatile tinnitus treatment Outcomes: A longitudinal follow-up study
Pulsatile tinnitus (PT) is characterized by the perception of a rhythmic sound that is in sync with the patient’s heartbeat, occurring in the absence of an external auditory stimulus. Representing approximately 4 % of tinnitus cases, PT has the potential to significantly impact both physical and mental well-being [1–3]. CT angiography and venography (CTA/V) is a significant imaging technique employed in the evaluation of the etiology of PT[4,5]. The etiology of PT is categorized into vascular an…
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Differences in advanced radiologic features of glioma subtypes under the 2021 WHO classification of tumors of the central Nervous system
The 2021 WHO Classification of Tumors of the Central Nervous System split gliomas within four families [1]. The gliomas are subclassified within the categories of Adult-type diffuse glioma, pediatric type diffuse low-grade glioma, pediatric type diffuse high-grade glioma, and circumscribed astrocytic glioma [2,3]. In this review, we synthesize findings on the different glioma subtypes within each category.
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Interpretable Machine learning model using Dual-Energy CT for predicting adverse histopathological status in gastric Cancer: A multicenter study
Gastric cancer (GC) ranks as the fifth most prevalent malignant neoplasm globally and is also the fifth leading cause of cancer-related deaths worldwide[1]. Advanced tumor stage (T3/T4), lymph node metastasis (LNM), and lymphovascular or perineural invasion (LVI/PNI) are strongly associated with poor clinical outcomes[2–5]. These prognostic factors reflect advanced-stage disease, in which patients are more likely to benefit from neoadjuvant therapy[6–8]. Recently, some scholars have proposed tha…
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Multimodal deep learning model for predicting microsatellite instability in colorectal cancer by contrast-enhanced computed tomography and histopathology
Colorectal cancer (CRC) ranks as the third most commonly diagnosed malignancy and the second leading cause of cancer-related deaths globally [1]. Despite advancements in surgery and systemic therapies, the intricate molecular heterogeneity of CRC continues to hinder biomarker-guided treatment stratification and precision oncology approaches [2]. Among the established molecular biomarkers in CRC, microsatellite instability (MSI) has emerged as a critical determinant of prognosis and therapeutic r…
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CT-based habitat radiomics for differentiating papillary thyroid carcinoma from nodular goiter: a two-center study
To develop habitat-based radiomics signatures for distinguishing papillary thyroid carcinoma (PTC) from nodular goiter (NG).