BACKGROUND AND PURPOSE:
Vein of Galen malformation (VOGM) is a rare fetal arteriovenous shunt with presentations ranging from asymptomatic in infancy to high-output cardiac failure and death. Prenatal percutaneous embolization is being explored in fetuses predicted to be at elevated risk of death in the Neonatal Intensive Care Unit (NICU). The purpose of this study was to evaluate the reliability of previously reported measurements and identify any novel imaging markers predictive of NICU mortal…
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Prediction of Neonatal Intensive Care Unit Mortality in Fetuses and Neonates with Vein of Galen Malformation [CLINICAL]
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Comparative Safety and Efficacy of Balloon-Mounted and Self-Expanding Stents in Rescue Stenting for Large Vessel Occlusion: Secondary Analysis of the RESCUE-ICAS Registry [RESEARCH]
BACKGROUND AND PURPOSE:
Patients with intracranial stenosis–related large-vessel occlusion (ICAS-LVO) may experience better outcomes with stent placement compared with stand-alone mechanical thrombectomy (MT). This study evaluates the safety and clinical outcomes of self-expanding stents (SES) versus balloon-mounted stents (BMS) in patients with ICAS-LVO treated with MT and stent placement.MATERIALS AND METHODS:
This secondary analysis of the Registry of Emergent Large-Vessel Occlusion D… -
Prospective MR Evaluation of Endolymphatic Hydrops at Multiple Flip Angles Using Single-Dose Gadolinium Contrast [RESEARCH]
BACKGROUND AND PURPOSE:
Technical advancements in inner ear MRI promise improved diagnosis and management of Ménière disease (MD), but a key challenge in optimizing 3D-FLAIR protocols for inner ear imaging lies in selecting the optimal flip angle. This study evaluates the 3 most common flip angle parameters used in 3D-FLAIR imaging for MD through a prospective, head-to-head comparison of image quality at constant flip angle (CFA) 120°, CFA 140°, and variable flip angle (VFA… -
Can CTA-Based Machine Learning Identify Patients for Whom Successful Endovascular Stroke Therapy Is Insufficient? [ARTIFICIAL INTELLIGENCE]
BACKGROUND AND PURPOSE:
Despite advances in endovascular stroke therapy (EST) devices and techniques, many patients are left with substantial disability, even if the final infarct volumes (FIVs) remain small. Here, we evaluate the performance of a machine learning (ML) approach by using pretreatment CTA to identify this cohort of patients that may benefit from additional interventions.MATERIALS AND METHODS:
We identified consecutive subjects with large vessel occlusion (LVO) acute ischemic str… -
Catheter-Vessel Interactions during Aspiration Thrombectomy: A Comprehensive Analysis Using a Novel Swine Model [RESEARCH]
BACKGROUND AND PURPOSE:
Catheter-vessel interactions during aspiration thrombectomy may vary depending on the vessel size, potentially affecting reperfusion outcomes. This study aimed to assess how vessel diameter influences procedural dynamics and reperfusion success rates by using a swine model with real-time, direct vessel visualization.MATERIALS AND METHODS:
We used an animal model of Yorkshire swine to evaluate catheter-vessel interactions during aspiration thrombectomy. The common caroti… -
How Has the Definition of Oligometastatic Disease Evolved?
The standard measure of lesion count may matter less than the underlying biology driving treatment response in oligometastatic disease. Medscape Medical News
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How Does Diabetes Affect Coronary Stent Success?
Among individuals in Sweden receiving second-generation drug-eluting stents, those with diabetes, particularly type 1 diabetes, have higher rates of stent failure than those without diabetes. Medscape News UK
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Benefits of Structured Lifestyle Program in US POINTER Trial
Beyond cognition, structured lifestyle delivers may also improve sleep apnea, blood pressure regulation and cognitive resilience, new data from US POINTER trial shows. Medscape Medical News
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Tumor and Perirenal Adipose Tissue Radiomic Models for Pathological T-Stage Prediction and Biological Exploration in Clear Cell Renal Cell Carcinoma
Clear cell renal cell carcinoma (ccRCC) shows a rising incidence and mortality worldwide [1,2]. Guideline-implemented cancer staging systems play an essential role in stratifying patients with tumors, especially in terms of therapeutics, prognostic prediction, postoperative follow-up, and even clinical trials. Notably, the T-stage system has shown great relevance in guiding clinical management decisions for ccRCC [3–5]. Hence, accurately predicting T staging preoperatively is crucial for optimiz…