People who live or have lived near Coldwater Creek, Missouri, have a higher risk of developing cancer.
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Gadolinium concentration dependent signal enhancement profiles using routine clinical sequences with gadopiclenol, gadoterate, gadobutrol, and gadoxetate at 1.5, 3 and 7 Tesla
Gadolinium-based contrast agents (GBCAs) are widely used in magnetic resonance imaging (MRI) to improve detection and characterization of pathological lesions [1–3]. The presence of current commercial GBCAs in tissues and body fluids most prominently changes images acquired with T1-weighted (T1w) contrast, due to a Gd-induced shortening of corresponding tissue- and fluid-water T1 times [4,5]. The agent-specific parameter that quantitatively captures this effect is the longitudinal molar relaxivi…
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Validation of artificial intelligence software for automatic calcium scoring in cardiac and chest computed tomography
The extent of coronary artery calcium (CAC), assessed on computed tomography (CT), is a strong predictor of cardiovascular events, providing essential data for cardiovascular risk discrimination and decision-making [1–4]. It is now also advised to assess coronary artery calcium on non-electrocardiogram (ECG)-synchronized chest CT, including low-dose chest CT for lung cancer screening (LCS) [5]. While visual evaluation is recommended, quantification of calcium can be considered by calculating the…
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Synthetic hematocrit-based extracellular volume quantification from photon-counting CT: Validation against MRI and systematic bias correction
Myocardial extracellular volume (ECV) is an established imaging biomarker for assessing myocardial fibrosis and interstitial disease, playing a crucial role in the diagnosis and risk stratification of conditions such as cardiomyopathies including amyloidosis, and ischemic heart disease [1,2]. Cardiac magnetic resonance imaging (MRI) has long been considered the reference standard for ECV quantification due to its ability to provide high-resolution tissue characterization through T1 mapping befor…
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Imaging Utilization Differences After Telemedicine Versus In-Person Visits
The COVID-19 pandemic resulted in a rapid expansion of telemedicine, but little is known about its impact on diagnostic imaging utilization. This study evaluates differences in imaging utilization after telemedicine versus in-person visits at the national level.
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A Simplex algorithm approach to determine the optimal keV and window setting for appendicitis visualization
Contrast-enhanced dual energy CT, with low-mono-energetic CT scanning (conventional 70 keV and low-mono energetic 40 keV) can improve visualization of acute inflammatory processes, but the high iodine attenuation often requires adjustment of window display settings to optimize interpretation. Here, we aim to determine optimal keV and window settings for the visualization of acute appendicitis from images derived from low-mono-energetic-CT.
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Explainable AI Model for Breast MRI Shows Effectiveness in High and Low Prevalence Breast Cancer Datasets
A fully convolutional data description (FCDD) model for identifying anomalies on breast MRI demonstrated an 84 percent AUC for detection tasks in a balanced cohort with a 20 percent malignancy prevalence and a 72 percent AUC for detection tasks in an imbalanced group with a 1.85 percent cancer prevalence.
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CMS' proposed 2026 MPFS rule would impact imaging
CMS has proposed its MPFS rule for 2026, and if finalized, it would affect imaging services in radiology, nuclear medicine, and…