The Planmed XFI full-body weightbearing cone-beam CT scanner reportedly enables upright and supine patient positioning.
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Severity Classification of Pediatric Spinal Cord Injuries Using Structural MRI Measures and Deep Learning: A Comprehensive Analysis across All Vertebral Levels [ARTIFICIAL INTELLIGENCE]
BACKGROUND AND PURPOSE:
Spinal cord injury (SCI) in the pediatric population presents a unique challenge in diagnosis and prognosis due to the complexity of performing clinical assessments on children. Accurate evaluation of structural changes in the spinal cord is essential for effective treatment planning. This study aims to evaluate structural characteristics in pediatric patients with SCI by comparing cross-sectional area (CSA), anterior-posterior (AP) width, and right-left (RL) width across… -
Mitigating Brain MR Imaging Degradation Due to Ferumoxytol Therapy in Patients with Iron Deficiency Anemia [RESEARCH]
SUMMARY:
Ferumoxytol, an FDA-approved treatment for iron deficiency anemia, is frequently used off-label as an MRI contrast agent. However, its unintended effects on brain MRI after anemia treatment, particularly in SWI and GRE sequences, remain insufficiently addressed. This study evaluates the optimal time interval between therapeutic ferumoxytol administration and brain MRI to minimize such effects. Analyzing 40 patients who underwent MRI within 3 months of ferumoxytol treatment, we found tha… -
Hybrid [18F] Fluoroestradiol Brain PET/CT/MRI for Detection of Estrogen Receptor-Positive Intracranial Metastases Compared with MRI and Vertex-to-Below the Knees PET Imaging [CLINICAL]
BACKGROUND AND PURPOSE:
[18F]-fluoroestradiol (FES) is a novel molecular imaging radiopharmaceutical that has demonstrated promise in the staging of ER-positive brain metastases. Our aim was to determine if hybrid [18F] FES brain PET/MRI is superior to conventional brain MRI alone for detecting estrogen receptor (ER)–positive brain and calvarial metastases, compare limited [18F] FES brain PET with vertex-to-below the knees [18F] FES PET results, and determine the impact of [18F] FES brain … -
Differentiation between Nonenhancing Tumor in Glioblastoma and Vasogenic Edema Using Diffusion-Weighted and Dynamic Susceptibility Contrast MR Imaging [RESEARCH]
BACKGROUND AND PURPOSE:
Differentiating nonenhancing glioblastoma from vasogenic edema remains a challenge in neuroimaging. This study evaluates the utility of diffusion-weighted and dynamic susceptibility contrast MR imaging, particularly ADC and relative CBV (rCBV), in distinguishing these entities.MATERIALS AND METHODS:
We retrospectively analyzed 111 patients diagnosed with glioblastoma with available pretreatment MRIs from January 1, 2022, to December 31, 2023, including 13 patients with … -
Clinical Use of the Swoop Portable MR Imaging System [CLINICAL]
We have a large clinical experience (>500 patients) with the ultra-low-field, portable brain MRI (Swoop Portable MR Imaging System, Hyperfine; www.hyperfine.io). This video article gives an overview of the scanner characteristics, scan procedure, and representative clinical images obtained from our experience. The portable MRI system is a useful adjunct to high-field MRI for critically ill patients, avoiding the time and risks associated with moving critically ill patients and their life supp…
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MR Imaging versus Noncontrast CT for Selecting Patients with Acute Ischemic Stroke of Large Vessel Occlusion for Endovascular Thrombectomy: A Systematic Review and Meta-Analysis [CLINICAL]
BACKGROUND:
Neuroimaging in the acute phases after the onset of stroke symptoms is necessary to determine large vessel occlusion presence as well as the extent of the ischemic insult before deeming eligibility for endovascular thrombectomy (EVT).PURPOSE:
To evaluate the clinical outcomes in patients with acute ischemic stroke selected for EVT based on initial imaging; NCCT compared with those selected by using MRI.DATA SOURCES:
PubMed, Embase, Scopus, and Web of Science were searched from in… -
Predicting 1p/19q Codeletion Status in Glioma Using MRI-Derived Radiomics: A Systematic Review and Meta-Analysis of Diagnostic Accuracy [RESEARCH]
BACKGROUND:
The 1p/19q codeletion is a key genetic marker in gliomas and plays a crucial role in prognosis and treatment decisions. Traditional methods for detecting this genetic alteration rely on invasive tissue biopsies.PURPOSE:
This systematic review and meta-analysis aimed to evaluate the performance of MRI-derived radiomics-based models to predict glioma 1p/19q codeletion status.DATA SOURCES:
A literature search was conducted in 4 databases: PubMed, Web of Science, EMBASE, and Scopus.
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Carotid Plaque-RADS: Inter- and Intrareader Agreement and Learning Curve Analysis in CTA [RESEARCH]
BACKGROUND AND PURPOSE:
Atherosclerotic disease of the carotid arteries is a major cause of ischemic stroke. Traditionally, the degree of stenosis has been regarded as the primary parameter for predicting stroke risk, but emerging evidence highlights the importance of carotid plaque composition and morphology. Recently, the Carotid Plaque-Reporting and Data System (RADS) has been introduced to standardize carotid plaque assessment beyond the degree of carotid stenosis. However, its reliability i… -
Association of MRI-Visible Perivascular Spaces with Early White Matter Injury [RESEARCH]
BACKGROUND AND PURPOSE:
MRI-visible perivascular spaces (PVS) are considered markers of cerebral small vessel disease (CSVD) and may reflect dysfunction of brain perivascular drainage. WM integrity assessed with DTI provides a sensitive assessment of early brain injury, related vascular risk factors, and risk of stroke and dementia. We investigated the relationship between PVS and WM integrity in community-dwelling participants.MATERIALS AND METHODS:
Framingham Heart Study (FHS) participants w…