Ultrasound-guided percutaneous liver biopsy (PLB) is widely applied in clinical practice as an indispensable tool, especially for radiologically indeterminate lesions [1,2]. The National Comprehensive Cancer Network (NCCN), the European Society for Medical Oncology (ESMO), and the Chinese Society of Clinical Oncology (CSCO) have all confirmed the value of PLB as a diagnostic strategy for liver lesions [3–6]. The biopsy specimens can provide tumor-specific characteristics, including histopatholog…