Colorectal cancer (CRC) ranks as one of the three most common malignancies worldwide, and the liver is the most frequent site of distant metastasis [1,2]. Colorectal liver metastases (CRLM) are a major cause of cancer-related mortality among patients with CRC [3]. Surgical resection is generally considered the standard, potentially curative treatment for resectable CRLM. However, because of limitations such as tumour number, size and location, the presence of occult micrometastases and impaired …