Development and validation of a CT-based deep learning radiomics model for differentiating parathyroid adenoma from atypical parathyroid tumor/parathyroid carcinoma

According to the 2022 World Health Organization (WHO) classification, parathyroid tumors are categorized into three subtypes: parathyroid adenoma (PA), atypical parathyroid tumor (APT), and parathyroid carcinoma (PC) [1]. APT and PC are extremely rare, together accounting for less than 2% of all parathyroid neoplasms [2]. APT is defined as a neoplasm of uncertain malignant potential, lacking definitive histopathological evidence of carcinoma. Most APTs share histological characteristics with PC,…

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