Dilation of the main pancreatic duct (MPD) is relative uncommon (0.2%) and can occur in a variety of benign and malignant conditions, each associated with distinct pathological mechanisms. Endoluminal obstruction due to intraductal stones as seen in chronic pancreatitis, or intraluminal growing tumors such as high-grade intraductal papillary neoplasms (IPMN) may be responsible for secondary MPD dilation. In recurrent acute and chronic pancreatitis, inflammation and subsequent fibrotic healing pr…