Head and Neck Squamous Cell Carcinoma (HNSCC) represents a notably diverse group of malignant neoplasms that arise from the mucosal epithelium found in the oral cavity, pharynx, and larynx. This type of carcinoma accounts for nearly 90 % of all tumors located in the head and neck region [1]. Globally, there are over 830,000 new cases of HNSCC each year and 430,000 deaths; the 5-year survival rate has long hovered around 40 %-60 % [2]. Current standard treatment regimens primarily involve surgica…