Population-based screening mammography has been proven to reduce breast cancer (BC) mortality by over 40 % [1,2]. In the current workflow, women recalled for further assessment of suspicious findings at first-level examinations undergo additional mammographic views, ultrasound, digital breast tomosynthesis, or even magnetic resonance imaging (MRI) to clarify suspicious findings [3]. However, these modalities and their combinations are limited by suboptimal specificity, referring to needle biopsy…