Brain-tumor interface-based MRI radiomics models to predict Ki-67 proliferation status of meningiomas: A multi-center study

Meningiomas are the most frequently occurring primary tumors within the central nervous system [1], and their biological diversity results in significant differences in treatment strategies and prognosis. Ki-67, a nuclear protein, is actively expressed during cell cycle phases such as G1, S, G2, and M, representing active cell division. During these phases, Ki-67 levels gradually increase, reflecting active cell proliferation, whereas it remains absent in the quiescent G0 phase. In meningiomas, …

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