T1-weighted subtraction maps improve the detection of contrast-enhancing lesions in multiple sclerosis

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disorder that results in axonal demyelination. It is the most common inflammatory disorder affecting the central nervous system and the leading cause of non-traumatic disability among young people in the Global North. Currently approximately 2.9 million people are diagnosed with MS worldwide, and the prevalence continues to rise.

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