Acute abdominal pain is one of the most common chief complaints encountered in the emergency department and outpatient setting. Across all sites, the left upper quadrant (LUQ) is the least common location for abdominal pain with reportedly the lowest physical examination interrater agreement. The limited sensitivity of physical examination, combined with an uncommon and nonspecific clinical presentation, make assessment of LUQ pain challenging. Acute LUQ pain may arise directly from the spleen o…