Multiple ground-glass nodules (GGNs) were defined as the presence of two or more GGNs within the lungs on computed tomography (CT). GGNs could be classified as either pure ground-glass nodules (pGGNs, without solid components) or mixed ground-glass nodules (mGGNs, containing solid components) [1,2]. Previous studies have demonstrated that GGNs that persist after 3–6 months of follow-up are strongly suggestive of primary lung adenocarcinoma [3–5]. However, existing studies on the evaluation and f…