The 2021 WHO Classification of Tumors of the Central Nervous System split gliomas within four families [1]. The gliomas are subclassified within the categories of Adult-type diffuse glioma, pediatric type diffuse low-grade glioma, pediatric type diffuse high-grade glioma, and circumscribed astrocytic glioma [2,3]. In this review, we synthesize findings on the different glioma subtypes within each category.