Deep-learning derived detailed measures of body fat distribution and cardiovascular outcomes in non-dialysis dependent chronic kidney disease: The multi-ethnic study of atherosclerosis

An obesity paradox, i.e., an association between high BMI and reduced all-cause mortality, has been reported in patients with non-dialysis-dependent chronic kidney disease (CKD). We have recently developed and validated a fully automated deep-learning algorithm that can automatically segment and quantify detailed muscle and fat distributions from any conventional chest CT. Here, we generated these robust biomarkers in a study cohort with non-dialysis-dependent CKD (eGFR 15–90 mL/min/1.73 m2, Sta…

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