Gastric cancer (GC) remained a significant global health concern, which ranked fifth in terms of incidence and fourth in mortality globally among malignant tumors [1]. In China, the incidence and mortality of gastric cancer ranked second among malignant tumors, and the incidence rate is increasing [2]. Surgery remains the main treatment for GC, but radical gastrectomy is only suitable for early-stage GC. Most GC patients are diagnosed with locally advanced gastric cancer (LAGC), with high recurr…