Imaging to risk-stratify patients with coronary artery disease (CAD) has shifted from the detection of myocardial ischemia and/or obstructive stenosis toward detecting and differentiating coronary plaque, which represents an earlier disease state.(1) Non-obstructive plaques usually do not cause anginal symptoms or myocardial ischemia, but do elevate the risk for future coronary events. Indeed, non-obstructive CAD at baseline accounted for most events in the PROMISE trial and ORFAN study.(2, 3) I…