TOC Summary This study investigated the relationship between periprocedural myocardial injury (PMI) and plaque volume assessed by coronary computed tomography angiography (CCTA). PMI is a common complication following percutaneous coronary intervention (PCI) and is associated with worse outcomes. We found that both total plaque volume and low-attenuation plaque volume, measured at target lesions and across all lesions per patient, were significantly higher in patients with myocardial injury afte…