Recent trials showed potential clinical benefit of fractional flow reserve (FFR) application in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI),1,2 however, the optimal FFR cut-off point still remains unclear in this clinical setting. Advances in computational methods facilitated non-invasive physiological assessment from coronary computed tomography angiography (CCTA), that may be especially beneficial in patients undergoing TAVI, allowing for the …