Abnormal adrenal gland size is closely associated with various diseases, including primary aldosteronism, Cushing’s syndrome, adrenal tumors, diabetes, cardiovascular diseases, and Hypothalamic Pituitary Adrenal (HPA) axis-related disorders[1–5]. Untimely diagnosis and intervention in primary aldosteronism and Cushing’s syndrome can increase the risk of cardiovascular disease and mortality by 1.5 to 10 times[6–9]. These disorders also significantly increase the risk of metabolic syndrome, partic…