The interesting paper by L. Deng et al. [1], which updates the diagnostic radiological imaging of neoplastic pseudocirrhosis (NPC) in breast cancer liver metastasis, merits further exploration from a pathophysiological perspective. This would help us to better understand this pathology, which often indicates an advanced stage of different neoplastic diseases. In order for a liver disease to be classified as an NPC, two criteria must be met: metastatic liver involvement and clinical signs that mi…