Hypersensitivity reaction (HR) is a subtype of adverse drug responses that are unpredictable and characterized by symptoms and/or signs triggered by a drug dose that is generally well tolerated by healthy individuals. Patients typically present with manifestations resembling allergic reactions, such as urticaria, pruritus, angioedema, erythema, and anaphylaxis [1,2]. With the increasing use of contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), contrast media (CM) ad…