BACKGROUND AND PURPOSE:
MRI-visible perivascular spaces (PVS) are considered markers of cerebral small vessel disease (CSVD) and may reflect dysfunction of brain perivascular drainage. WM integrity assessed with DTI provides a sensitive assessment of early brain injury, related vascular risk factors, and risk of stroke and dementia. We investigated the relationship between PVS and WM integrity in community-dwelling participants.
MATERIALS AND METHODS:
Framingham Heart Study (FHS) participants w…