Enlarged choroid plexus is associated with reduced gray matter volumes and increased plasma amyloid-beta: a population-based study of older adults

The choroid plexus (ChP) is a highly vascularized structure comprising a monolayer of epithelial cells with microvilli that surrounds connective tissue and permeable capillaries in the brain ventricles [1]. The ChP is known to play a crucial role in producing cerebrospinal fluid (CSF) and in forming a permeability-regulating barrier between the blood and the CSF, known as the blood-CSF barrier [2]. Evidence has emerged that ChP volume is increased in patients with neurodegenerative disorders and…

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