Knee osteoarthritis (KOA) is the most common degenerative disease affecting cartilage, meniscus, synovium, and subchondral bone [1]. By the questionnaire method, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) can quantitatively evaluate the pain in KOA patients [2]. As the gold standard for diagnosing radiographic KOA (RKOA), the Kellgren and Lawrence grades (KLGs) are usually used in clinical practice based on the knee X-ray images [3]. However, only a clear image of…