A Method for Imaging the Ischemic Penumbra with MRI Using Intravoxel Incoherent Motion [RESEARCH]

BACKGROUND AND PURPOSE:
In acute ischemic stroke, the amount of “local” CBF distal to the occlusion, ie, all blood flow, whether supplied antegrade or delayed and dispersed through the collateral network, may contain valuable information regarding infarct growth rate and treatment response. DSC processed with a local arterial input function (AIF) is one method of measuring local CBF (local-qCBF) and has been shown to correlate with collateral supply. Similarly, intravoxel incoherent motion MRI (…

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