Decreased wall shear stress on 4D-flow-MRI is associated with wall instability of unruptured intracranial aneurysm

The wall instability of unruptured intracranial aneurysms (UIAs) is associated with aneurysm growth or rupture. The wall shear stress (WSS) of 4D-flow-MRI can indicate hemodynamic abnormalities on the aneurysm wall. Aneurysm wall enhancement (AWE) of vessel wall MRI (VWI) and volume transfer constant (Ktrans) of dynamic contrast-enhanced MRI (DCE-MRI) can indicate inflammation and permeability changes of the unstable aneurysm wall. We hypothesize that the WSS of UIAs is not only associated with …

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