Stroke Thrombectomy for Large Infarcts with Limited Penumbra: Systematic Review and Meta-Analysis of Randomized Trials [CLINICAL]

BACKGROUND:
Recent randomized trials have suggested that endovascular thrombectomy (EVT) is superior to medical management (MM) for stroke patients with large infarcts. However, whether or how perfusion metrics should be used to guide optimal patient selection for treatment is unknown.

PURPOSE:
To synthesize trial results to provide more definitive guidance on the role of EVT for stroke patients with large infarcts based on perfusion metrics.

DATA SOURCES:
MEDLINE database from inception up to…

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