Hyperperfusion and Blood-Brain Barrier Disruption beyond the Diffusion-Restricted Infarct 1 Day after Successful Mechanical Thrombectomy [NEUROVASCULAR/STROKE IMAGING]

BACKGROUND AND PURPOSE:
Patterns of the cerebral microcirculatory response with changes in the BBB and perfusion in patients with stroke and a large vessel occlusion are still unclear. We combined dynamic contrast-enhanced (DCE) permeability and DSC perfusion MRI to detect such patterns beyond the borders of the diffusion-restricted infarct core after successful recanalization.

MATERIALS AND METHODS:
Combined DCE permeability and DSC perfusion MRI were performed prospectively in patients within…

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